Searchable abstracts of presentations at key conferences on reproductive biology and medicine

ra0002o014 | SRF Student Prize Session | SRF2015

Maternal protein restriction around conception reduces the neural stem cells during mouse fetal brain development and alters neuronal differentiation during gestation

Gould Joanna Mary , Fleming Tom , Airey Chris J , Marfy-Smith Stephanie Jane , Willaime-Morawek Sandrine

Maternal malnutrition during pregnancy is detrimental to fetal development and increases the risk of many chronic diseases in later life i.e. neurological consequences such as increased risk of schizophrenia. Previous studies have shown maternal protein malnutrition during pregnancy and lactation compromises brain development in late gestation and after birth, affecting structural, biochemical, and pathway dynamics with lasting consequences for motor and cognitive function. Ho...

ra0001p025 | Stem cells and reprogramming | WCRB2014

The role of maternal low protein diet on neural stem cells and neurogenesis in the offspring brain?

Airey Chris J , Smith Phoebe J , Gould Joanna M , Marfy-Smith Stephanie J , Fleming Tom P , Willaime-Morawek Sandrine

Globally, malnutrition is the single greatest threat to public health. Maternal malnutrition during pregnancy is detrimental to foetal development and increases the risk of many chronic diseases in later life. Neurological consequences include increased risk of schizophrenia and abnormal anxiety-related behaviour. Previous studies have shown that maternal protein restriction has a negative effect on foetal brain development in vivo and we previously showed an effect o...